Product description

Osphos Injection is an injectable bisphosphonate solution for intramuscular use in horses only.

Active ingredients

Each Osphos Injection mL contains:

• Clodronate disodium 60 mg
• Sodium hydroxide (to adjust pH)
• Water for injection

Indications for use

Osphos Injection is indicated for the control of clinical signs associated with navicular syndrome in horses.

Administration and dosage

• Administer 1.8 mg/kg by intramuscular injection up to a maximum dose of 900 mg per horse. Divide the total volume evenly into three separate injection sites. Discard unused vial contents. Osphos Injection is provided in a single use vial and does not contain a preservative.

• Clinical improvement is most evident at 2 months post-treatment. Of the horses that responded to treatment with Osphos Injection in the field study, 65% maintained their level of improvement through the 6 month evaluation.

• If there is no response to initial therapy, the horse should be re-evaluated. For horses that initially respond to Osphos Injection but do not maintain their clinical improvement for 6 months, Osphos Injection may be re-administered at 3 to 6 month intervals based on recurrence of clinical signs.

• For horses that respond to Osphos Injection and maintain clinical improvement for 6 months, Osphos Injection should be re-administered after clinical signs recur.

Prescribing information